Best Fat Soluble B1

What is Benfotiamine?

Benfotiamine is a supplemental version of the bioavailable, body-made nutrient, Thiamine. It is classified as a B1 vitamin. This substance is a fat-soluble B vitamin. Fat soluble vitamins are soluble within lipids, and are absorbed in fat globules inside the body that are then circulated in the circulatory system.
In nature, the presence of thiamine can be found within legumes, and fortified grain products such as bread, cereal, rice, or flour.

What does ‘NusaPure Benfotiamine 300mg’ do?

Benfotiamine has many notable nutritional benefits for both men and women. For one, it is best known for its supporting role within the blood stream. Once inside the body, it works to increase insulin levels while breaking down sugar for energy.* This positively impacts blood sugar within the body.* In fact, it can act as a blood sugar supplement.*

Aside from sugar levels, Benfotiamine plays an active role inside the brain. It’s known to fight off free radicals leading to protection of brain cells.* It’s a super addition to any lifestyle to act as cognitive supplement for daily use.*

Why should YOU choose NusaPure?
– Capsules that are easy to swallow and odorless 
– Pure extract with a maximum strength formula 
– Completely all natural complex with no sugars, salts, starches, gluten, soy or milk 
– Ingredient with clinical study support
– NusaPure is a trusted brand – recognized by Amazon for our excellent customer service –
– Made in the USA, in FDA inspected and GMP certified facilities
– 3rd party lab tested and verified for purity and safety

Alpha-lipoic acid is a sulfur-containing fatty acid that performs vitamin-like roles in the body. Also known as thioctic acid or simply lipoic acid (LA), this compound functions as a coenzyme in the metabolism of carbohydrates, and was originally thought to belong to the B vitamin family. LA is required for synthesis of acetyl CoA, a pivotal metabolite in the cellular process of transforming glucose (blood sugar) into energy. Since amounts of alpha-lipoic acid in supplements are up to 1000 times greater than the amounts of LA that could be obtained by diet, supplemental LA can introduce physiologic actions that food alone would not bestow. An intensively researched compound, alpha-lipoic acid taken orally is thought to go beyond its role as a metabolic cofactor and instead elicit a unique set of biochemical activities that can safely enhance many areas of health. Benfotiamine is a synthetic derivative of thiamin that has been shown in many studies to be far more bioavailable than actual thiamin. Benfotiamine taken orally is readily absorbed at higher doses, which is in sharp contrast to regular water-soluble forms of thiamin that exhibit a rapid decline in absorption when taken in doses above 5 mg. Human and rodent studies indicate that benfotiamine can greatly improve thiamin status, especially in comparison with regular forms of thiamin.

Benfotiamine

Support against oxidative stress. Benfotiamine displays direct antioxidant action in vitro, and preliminary research with human subjects suggests that this activity can be advantageous in helping to safeguard the integrity of human DNA by increasing the antioxidant capacity of plasma. In the laboratory, when human, rat, and porcine kidney cells were exposed to toxins that assault the integrity of DNA, benfotiamine was able to reduce oxidative stress under these circumstances. Benfotiamine, like vitamins C and E, can deter the activation of NF-kB (a DNA-binding factor known to be activated by oxidative stress-generated reactive oxygen species) for more balanced immune responses. Furthermore, recent in vitro results suggest that the beneficial antioxidant properties of benfotiamine could work against some forms of lipid peroxidation. An animal model suggests that during oxidative stress generated by excess glucose, benfotiamine has the capacity to reduce levels of superoxide and hydroxyl radicals in the heart. Similarly, an animal model of induced oxidative stress in the cerebral cortex (the outer most layer of the brain) suggests a beneficial antioxidant effect of benfotiamine. Supports blood levels of thiamin pyrophosphate (TTP), the biologically active co–enzyme form of thiamin* Helps maintain healthy glucose metabolism. Benfotiamine increases blood and tissue levels of thiamin pyrophosphate (TPP), the biologically active co-enzyme form of thiamin. TPP acts as a co-enzyme for three critical enzymes involved in glucose metabolism: 1) transketolase, 2) pyruvate dehydrogenase, and 3) a-ketoglutarate decarboxylase. The latter two enzymes are involved in utilizing glucose for fuel. Thus, TTP is vital to the cell’s energy supply. Stimulates transketolase, a cellular enzyme essential for maintenance of normal glucose metabolic pathways. Supports healthy aging. Disrupts formation of Advanced Glycation End-Products (AGEs). Helps maintain healthy circulation.